Product name: |
Oxytetracycline Hydrochloride |
Synonyms: |
Oxytetracycline hydrochloride;Engemycin;Oxytetracycline hydrochloride;Mepatar; |
CAS: |
2058-46-0 |
Description |
yellow crystalline powder;odorless;bitter taste;with moisture;gradually darkens in light;alkali solution is easy to fail; It is a broad-spectrum bacteriostatic agent. |
Chemical formula |
C22H25ClN2O9 |
Uses:
Oxytetracycline hydrochloride is a broad-spectrum bacteriostatic agent, many Rickettsia, Mycoplasma genus, chlamydia, spirochetes, amoeba protozoa and some malaria parasites are also sensitive to this product. Enterococcus is resistant to Antibiotic Oxytetracycline Hydrochloride. Other such as actinomycetes, Bacillus anthracis, Listeria monocytogenes, Clostridium, Nocardia, Vibrio, Brucella, Campylobacter, Yersinia are sensitive.
Oxytetracycline Hydrochloride, like other tetracyclines, Antibiotic Oxytetracycline Hydrochloride is used to treat many infections, both common and rare (see Tetracycline antibiotics group). Antibiotic Oxytetracycline Hydrochloride is sometimes used to treat spirochaetal infections, clostridial wound infection and anthrax in patients sensitive to penicillin. Oxytetracycline is used to treat infections of the respiratory and urinary tracts, skin, ear, eye and gonorrhoea, although its use for such purposes has declined in recent years due to large increases in bacterial resistance to this class of drugs. The drug is particularly useful when penicillins and/or macrolides cannot be used due to allergy. Many species of Rickettsia, Mycoplasma, Chlamydia, Spirochetes, Amoeba and some Plasmodium are also sensitive to this product. Enterococcus is resistant to it. Others such as Actinomyces, Bacillus anthracis, Listeria monocytogenes, Clostridium, Nocardia, Vibrio, Brucella, Campylobacter, Yersinia, etc. are sensitive to this product.
Oxytetracycline is especially valuable in treating nonspecific urethritis, Lyme disease, brucellosis, cholera, typhus, tularaemia. and infections caused by Chlamydia, Mycoplasma and Rickettsia. Doxycycline is now preferred to oxytetracycline for many of these indications because it has improved pharmacologic features. Oxytetracycline can also be used to correct breathing disorders in livestock. Antibiotic Oxytetracycline Hydrochloride is administered in a powder or through an intramuscular injection. Many livestock producers apply oxytetracycline to livestock feed to prevent diseases and infections in cattle and poultry.
Specifications:
Name |
Antibiotic Oxytetracycline Hydrochloride |
|
Characters |
Yellow, Crystalline Powder |
|
Solubility |
Freely soluble in water, Sparingly soluble in alcohol |
|
pH |
2.3~2.9 |
|
Specific optical rotation |
-188~-200 |
|
Specific absorbance |
270~290 |
|
Light |
430nm |
≤0.50 |
490nm |
≤0.20 |
|
Related substances (%) |
Impurity A |
≤0.5 |
Impurity B |
≤2.0 |
|
Impurity C |
≤2.0 |
|
Total of impurities D. E and F |
≤2.0 |
|
Disregard limit |
≤0.1 |
|
Heavy metals (ppm) |
≤50 |
|
Water(%) |
≤2.0 |
|
Sulfated ash(%) |
≤0.5 |
|
Assay (%) |
95.0~102.0 |